Leucas aspera nanomedicine shows superior toxicity and cell. It is pungently aromatic and commonly used as an antipyretic herb in south india. This study was aimed to develop an efficient protocol for micropropagation of leucas aspera using nodal explants. Introduction excessive amounts of these free radicals can. Many plants and herbs hold their prestigious position in the field of medicine. The healing properties of plants have been transferred within the human communities for over the centuries. Title plant resources of southeast asia publication author. A total of species belo hedge leucas capitata desf. Leucas aspera material was collected from gangapur dam, nasik, maharashtra, india. This plant is an annual herb commonly found at roadsides and.
Pharmacological and medicinal uses of achyranthes aspera saba hasan amity institute of biotechnology, amity university, lucknow u. Aiton, locally known as gatathumba, as most widely distributed species. The crude methanol extract of leucas aspera leaves showed strong 1,1diphenyl2picrylhydrazyl ddph and superoxide radicalscavenging activities compared to other polaritybased extracted fractions. Conventionally, it is also used as an antipyretic and insecticide. Narasimhan, centre for floristic research, department of botany, madras christian college, tambaram. Leucas aspera, is a herb is widely distributed in tropical asia, africa and grows in highland crop fields, homesteads, fallow lands and roadsides3. Elemental analysis of leucas aspera semantic scholar. Mar 27, 2020 leucas aspera medicinal uses pdf march 27, 2020 leucas aspera commonly known as thumbai is distributed throughout india from the effects. Leucas aspera nanomedicine shows superior toxicity and.
Leucas aspera, diuretics activity, lipchitz method, laxative activity, furosemide, agaragar. Plant tissue culture has paved way for the production of both pathogenfree plants and secondary metabolites in large scale. Phytochemical evaluation and in vitro antioxidant activity. Leucas species leucas aspera name synonyms leucas dimidiata roth spreng. Leucas aspera at gandipet, hyderabad, ap w2 img 9054. Leucas aspera is an erect, annual plant with a muchbranched stem 30 60cm tall310. Structure of leucasin isolated from leucas aspera leaves.
Phytochemical studies on leucas aspera journal of chemical and. The present study was aimed to evaluate the antidiabetic and antioxidant activity of polar and nonpolar solvent extracts of leucas aspera willd. The rats were housed in clean polypropylene cages and fed with commercial amruit rat feed and water ad libitum. Studies on larvicidal and pupicidal activity of leucas aspera.
Leucas aspera belongs to the family lamiaceae commonly known as. Leucas aspera is reported to have antifungal, prostaglandin inhibitory, antioxidant, antimicrobial, antinociceptive and cytotoxic activities. Mar 05, 2020 last update on medicinxl wikipedia, the free encyclopedia. The free radical scavenging and antioxidant activity of petroleum ether, ethanol, isopropyl alcohol, ethyl acetate and chloroform extracts of l. They were properly washed in tap water and rinsed in distilled water and dried in an oven at a temperature of 35 40 0 c for 3 days and pulverized using a mortar and. Investigation of the inhibitory fraction of leucas aspera on prostaglandininduced contraction in guinea pig ileum provided four new diterpenes, leucasperones a 1 and b 2 and leucasperols a 3 and b 4, and three new isopimarane glycosides, leucasperosides a, b, and c 5.
The extract showed a significant free radical scavenging activity with an ic50 of. It is a small erect, much branched annual herb grows up to 60 cm in height. Link is an accepted name this name is the accepted name of a species in the genus leucas family lamiaceae. Lamiaceae labiatae according to the rules of icbn the names of the families should end in aceae.
Phytochemicals can play the role to scavenge these excess free radicals. The free radical scavenging activity of the methanol and aqueous extracts of leucas aspera leaves, based on the scavenging activity of the stable free radical 1,1 diphenyl2 picrylhydrazyl dpph were determined by mixing of 0. Plants are being used from more than years to treat diseases. Leucas aspera, antioxidant, free radical and cytotoxicity 1.
Vijayaraj and swarnakala department of marine biotechnology, amet university, kanathur, chennai 603112, tamilnadu, india. Among the four regions, leucas aspera from jagityala region contains more phenolic content 48. In vitro micropropagation and comparative free radical. Herbal medicines are widely used since time immemorial indicating that herbs are a growing part of modern, hightech medicine. Free radicals are involved in the body in normal metabolism, but their excess may harm and contribute to various disease like cancer, diabetes, parkinsons disease, cardiovascular problems, etc. Isolation and identification of nicotine from leucas aspera willd indian j pharm sci. Pharmacognostic and in vitro anti diabetic activity on aerial. Phytol a chemical constituent of leucas aspera through. Methanolic extract of whole plant exhibited dpph free radical scavenging.
Diterpenes from leucas aspera inhibiting prostaglandin. However, free flavonoid baicalein was reported in the ethereal fraction of hydro methanolic extract of leucas. Leucas aspera commonly known as thumbai is widely distributed throughout india from the himalayas down to ceylon. This file is licensed under the creative commons attributionshare alike 4. The plants have been reported to have antiinflammatory, analgesic, antidiarrheal, antimicrobial, antioxidant, and insecticidal activities. As of march 2014 the plant list recognises 3 accepted species including. Herbal medicines are having minimal adverse effects when compared to the available synthetic drugs to treat such chronic diseases and disorders. A novel phenolic compound from leucas aspera spreng.
Herbal medicine is one of the oldest valuable bestowals that was given to mankind. Introduction excessive amounts of these free radicals can lead to cell injury and death, which results in many diseases such as cancer, stroke. Acute toxicity study was carried out for fresh juice of leaves of leucas aspera with doses 2, 4. Although the species has many different common names depending on the region in which it is located, it is most commonly known as thumbai malayalam. Leucas aspera commonly known as thumbai is distributed throughout india. The plant is used traditionally as an antipyretic and insecticide. It contains over 200 species, widespread over much of africa, and southern and eastern asia iran, india, china, japan, indonesia, etc. In evaluation of diuretic activity male albino rats were used as the experimental animals. Chemical composition, in vitro antimicrobial, freeradicalscavenging and antioxidant activities of the. Ts of leaf passing through the midrib is broadly convex on the lower side and slightly grooved or flat on the upper side, a centrally located conjoint and collateral meristele associated with a parenchymatous pericycle layer on lower side, collenchymatous tissue underneath both the.
Antioxidant anticancer activity of leucas aspera extract and. Antioxidant properties of a novel flavonoid from leaves of. The plant, leucas aspera willd link is well known for its varied medicinal uses. The activityguided repeated fractionation of the methanol extract by silica gel column chromatography yielded a compound that. This study was undertaken to investigate diuretic and laxative potency of leucas aspera whole plant. Plant details information about leucas aspera plant. The juice from the leaves is used as an external application for psoriasis and painful swellings. Diterpenes from leucas aspera inhibiting prostaglandininduced contractions. Rjpt phytochemical composition and in vitro antioxidant. Leaves are subsessile or shortly petiolate, linear or linearly lanceolate, obtuse, pubescent up to 8. Jun 08, 2011 it is a small erect, much branched annual herb grows up to 60 cm in height.
In vitro antidiabetic activity of polar and nonpolar solvent. Pdf leucas aspera commonly known as thumbai is distributed throughout india from the. Permission is granted to copy, distribute andor modify this document under the terms of the gnu free documentation license, version 1. The mode of antimicrobial action of the essential oil of melaleucaalternifolia tea tree oil. Leucas is a genus of plants in the family lamiaceae, first described by robert brown in 1810.
Leaves sub sessile, linearlanceolate, obtuse, and entire. It also strongly inhibited the peroxidation of lipids. The plant is used to treat many diseases such as cough,cold diarrhea,inflammatory diseases. In sri lanka, six species exist with leucas zeylanica l. The record derives from wcsp data supplied on 20120323 which reports it as an accepted name record 111632 with original publication details. Leucas aspera is widely use d as foods and also for nutr itional requirement in countryside which was reported to have high protein content of 21. It has many vernacular names depending on the region and most commonly known as thumbai. An update of leucas aspera a medicinal plant ijsrm. The whole plant is used for different medicine in ayurveda thumba is a flower of kerala,it signifies purity. Pelagia research library procured from raj biotech india pvt. Leucas aspera is a plant species within the genus leucas and the family lamiaceae. The dried whole plant leaves, stems, and flowers material was subjected to extraction by continuous hot percolation method.
If you would like to support this site, please consider donating. Thus the new name for the family labiatae became lamiaceae. Leucas revealed the presence of tannins, alkaloids and glycosides ramya et al. It was selected for purification of the bioactive compound.
Jul 09, 2019 antimicrobial activity of leucas aspera pdf both the extracts exhibited a significant antibacterial activity against all the screened microorganisms. Last update on medicinxl wikipedia, the free encyclopedia. Lipophilic extracts of leucas zeylanica, a multipurpose. Pharmacognostic and in vitro anti diabetic activity on. Media in category leucas aspera the following 95 files are in this category, out of 95 total.
Studies on larvicidal and pupicidal activity of leucas. Leucas aspera, leucas zeylanica, antifungal, dermatophytes. Leucas aspera is an annual, branched, herb erecting to a height of 1560 cm with stout and hispid acutely quadrangular stem and branches. Preliminary chemical examination of some compounds in the different parts of the genus leucas.
The scavenging activity of these extracts was lower compared with both antioxidants, bht to evaluate antioxidant, antimicrobial and cytotoxic activity of different parts root, flower, leaf and. Introduction leucas aspera belonging to the family labiate is wellknown for its wide medicinal applications fig. Aiton is a popular, multipurpose medicinal plant in sri lanka but the pharmacological potential and the chemical profile have not been systematically investigated to understand and rationalize the reported ethnobotanical significance. Leucas aspera were collected from kottayam and authenticated. Leucas aspera commonly known as thumbai, gumma is found all over india. Plant tissue culture has paved way for the production of both pathogen free plants and secondary metabolites in large scale. A few uploads earlier identified as leucas cephalotes anti bacterial activity of leucas aspera leaf extract against micrococcus pyogenes and escheria coli have also been reported rastogi and mehrotra details of some important contributors. Acute toxicity study was carried out for fresh juice of leaves of leucas aspera with doses 2, 4 and 6mlkg with water.
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